Automatically deleting a specific file in windows 7 when running a specific program

I was wondering if there's a way to set up windows 7 so that it automatically deletes a specific file when i run a specific program?

The reason i'm asking this is because i've been trying to play a game on my computer but it won't run unless i delete a specific file in one of its folders. that is, I have to delete that file before I play the game each time. In case you've been wondering, I've contacted their customer support and it's been over a week, so i'm searching for other solutions over here.

Thanks.